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SeedBRx®

As the name suggests, SeedBRx® is your starting point for large-scale bioprocessing. Designed to produce high-quality seed cultures for larger bioreactors like CellBRx®, SeedBRx® simplifies cell expansion, trypsinization, and harvest processes. With its advanced Dynamic Bed Reactor (DBR) technology, it ensures efficient cell growth and seamless transfer to larger systems, making it the ideal solution for scaling up your bioprocessing operations.
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Scale Variants of​

SeedBRx® Bioreactors

Our product is available in various volume ranges, each tailored to meet your specific bioprocessing needs. Explore our volume range of SeedBRx® bioreactors:

5L SeedBRx®

The 5L SeedBRx® tackles the challenges of transitioning from small-scale research to medium-scale production. It bridges the gap between R&D and manufacturing by offering a versatile platform for pilot studies and process optimization. This system solves the problem of inconsistent cell yields and process variability by providing homogeneous mixing, precise control over critical parameters, and efficient trypsinization, ensuring high-quality seed cultures ready for transfer to larger bioreactors.

10L SeedBRx®

The 10L SeedBRx® addresses the challenges of large-scale seed culture production, where maintaining cell quality and consistency is critical. It solves the problem of inefficient scaling by offering a robust platform for producing high-density cell cultures at a larger volume. With its advanced automation and customizable perfusion controls, the 10L SeedBRx® ensures seamless cell expansion and harvest, preparing cells for transfer to commercial-scale bioreactors like CellBRx® with minimal loss and maximum viability.

Key Features & Advantages

Discover the features that make the SeedBRx® preferred choice for bioprocessing:

  • Single-Use Technology

    SeedBRx® utilizes single-use bioreactor technology, reducing the risk of cross-contamination and eliminating the need for time-consuming cleaning and sterilization processes. This also minimizes waste and operational costs.

  • User-Friendly Interface

    The intuitive SCADA software and touchscreen interface make SeedBRx® easy to operate, even for users with limited experience. Real-time monitoring and data logging ensure full control over the bioprocessing workflow.

  • Customizable Trypsinization

    The system includes an automated trypsinization module that allows for customizable protocols, ensuring efficient cell detachment with high viability. This feature simplifies the harvest process and prepares cells for seamless transfer to larger bioreactors like CellBRx®.

  • Seamless Integration with CellBRx®

    SeedBRx® is designed to work hand-in-hand with CellBRx®, ensuring a smooth transition from seed culture production to large-scale manufacturing. This integration simplifies scale-up challenges and maintains cell quality throughout the process.

Applications

SeedBRx® is a versatile bioreactor system designed to support a wide range of bioprocessing applications:
  • Vaccines

    Vaccines

    Scalable bioreactors ideal for inactivated and viral vector-based vaccine production - supporting both research & commercial cGMP operations.

  • Viral Vectors

    Viral Vectors

    Designed for high-yield production of Lentiviral & AAV vectors, bioreactor systems ensure controlled productivity from bench to clinical scale.

  • Stem Cells

    Stem Cells

    Single-use bioreactors designed for consistent expansion and cell recovery of stem cells in adherent & suspension formats.

  • Exosomes

    Exosomes

    Precision-engineered systems tailored for scalable exosome production and harvest, enabling consistent particle yield at large scale.

  • Therapeutic Proteins & Hormones

    Therapeutic Proteins & Hormones

    Versatile bioreactor systems for recombinant protein expression in mammalian hosts, ensuring consistent process control and production yield.

  • Cultured Meat

    Cultured Meat

    Bioreactors built for scalable production of animal cell-based meat, supporting myoblast, adipocyte, & scaffold-associated tissue growth under cGMP.

Technical Support Documents

We provide comprehensive technical support to help you get the most out of your SeedBRx® system. Explore our resources, including:

  • Brochures
  • Application Notes
  • Specification Sheets
  • Webinars
  • Scientific Resources
  • User Guides & Manuals

Do You Need A Demo?

Get expert guidance for your biotech needs. Our seasoned professionals offer tailored solutions to propel your bioprocessing endeavors forward.

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Frequently Asked Questions

What is the basic difference between CellBRx and SeedBRx bioreactors?

Both, the CellBRx and the SeedBRx bioreactor platforms are designed to support adherent cell culture, but they serve distinct purposes within the bioprocess workflow. CellBRx is a dynamic-bed bioreactor system specifically optimized for production-scale applications, offering large surface area (1 m² to 1500 m²) for high-density cell growth and biologics manufacturing. It is ideal for cGMP-scale production of viral vectors, vaccines, recombinant proteins, and cell therapies, where precise control and scalability are critical. In contrast, the SeedBRx platforms is engineered for expansion of adherent cells and live cell harvesting using automated trypsinization protocols—also functioning as a seed train platforms that provides a compact and efficient method to generate the required inoculum for CellBRx or other production bioreactors. SeedBRx units are typically smaller in scale (i.e 1L, 5L or 10L) and designed to maintain the same surface characteristics and flow dynamics as CellBRx, ensuring a smooth and consistent scale-up without requiring process re-optimization. Together, they form a streamlined and integrated upstream bioprocessing solution.

What Are the Scale Variants Available with the SeedBRx Bioreactor Platform?

The SeedBRx bioreactor platform is available in multiple scale variants to support seamless cell expansion across different process stages. Currently, OmniBRx offers SeedBRx units with 1L, 5L & 10L bioreactor systems (volumetric variants) with surface areas ranging from 0.5 m² to 50 m², providing flexible options for early-stage seeding, process development, and inoculum generation. While the 5L and 10L bioreactor systems are defined as standalone SeedBRx platforms, the 1L scale SeedBRx platform can optionally be converted from the 1L CellBRx bioreactor system by installing additional accessories like a Trypsinization module.

What Are the Different Applications for SeedBRx Bioreactor Platforms?

The primary use of SeedBRx bioreactors is in Integrated Seed Train (IST) processing, where they serve as a scalable and controlled environment to generate high-quality inoculum for larger bioreactors like CellBRx 50L & 200L. Integration of SeedBRx eliminates the need for manual cell expansion activities in 2D devices, reduces contamination risks, and ensures consistent cell health and density. Additionally, SeedBRx platforms are well-suited for stem cell cultivation and harvesting, offering a gentle, low-shear environment that supports the expansion and recovery of sensitive cell types such as MSCs, iPSCs, and hESCs. The design ensures uniform cell attachment and nutrient distribution, while the closed single-use format facilitates compliance with GMP standards. Whether used for upstream seed generation or stem cell therapies, SeedBRx delivers reliability, flexibility, and scalability for diverse cell-based applications.

How Can I Contact a Technical Expert at OmniBRx, and Can I Request a Live Demo of the SeedBRx System?

You can reach out to our technical team at OmniBRx by filling out the contact form on our website or by emailing us directly at info@omnibrx.com or Sales@omnibrx.com. Our team of application specialists and process engineers will promptly get in touch to understand your specific requirements and provide expert guidance on the SeedBRx bioreactor system. Yes, we do offer live demonstrations of the SeedBRx platform - either virtually or on-site at our Application Lab or customer facility (subject to availability). These demos provide a hands-on overview of system features, setup, operation, and performance metrics, tailored to your bioprocess needs. To schedule a demo, click “Need A Live Demo? Tab or simply mention your interest in your inquiry, and our team will coordinate the next steps.

Can the OmniBRx Team help us design and setup SeedBRx platforms for our process application?

Yes, the OmniBRx team offers complete support in designing, configuring, and implementing SeedBRx platforms tailored to your specific process requirements. Whether you're developing a new adherent cell culture process or looking to replace manual seed train steps, our team will work closely with you to understand your application, cell line characteristics, and scalability needs. From customizing bioreactor specifications to integrating SeedBRx into your existing workflow, we provide end-to-end assistance—including process mapping, installation, training, and technical validation. Our goal is to ensure that your SeedBRx setup delivers optimal cell yield, operational efficiency, and regulatory compliance—paving the way for a streamlined, closed, and scalable seed train process.

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