Ready-to-use, pre-sterilized bottle assemblies seamlessly connect to CellBRx SUBs -eliminating manual glassware prep and autoclaving for streamlined, contamination-free operations.
Precision-driven Peristaltic pump module seamlessly integrated with the CellBRx docking station for controlled fluid transfer and perfusion based close-loop bioprocessing.
Single-use, pre-sterilized vessels engineered for optimal cell growth, scalability, and hassle-free bioprocessing.
A compact, plug-and-play platform designed for seamless integration and secure operation of CellBRx bioreactor vessels.
SCADA-based bioreactor controller powered by Process-To-Gather software, enabling precise process control and real-time data acquisition.
Designed for adherent cell culture, the scale variants of CellBRx® platform deliver seamless process development and scale-up within a unified control architecture.
The CellBRx® 350 mL Quad bioreactor system is a compact, small-scale, multi-bioreactor platform tailored for high-throughput upstream process development, optimization, and characterization of adherent cell-based bioprocesses. Ideal for applications such as vaccine development, viral vector production optimization and process troubleshooting, exosome generation, and stem cell cultivation, it enables parallel operation of up to 8 single-use bioreactor vessels via 2× Quad docking stations connected to a SCADA-based process controller unit. The system offers precise control over critical parameters and supports robust, data-rich experimentation in mini-scale format.
The CellBRx® 1L bioreactors are compact, high-throughput system for early-stage adherent cell culture based vaccine and viral vector development. Its scalable disc-shaped carriers offer 1 m²and 2.5 m² versions to enable flexible process optimization. By emulating the principles of large-scale Dynamic Bed Reactor (DBR) technology in a miniature format, the CellBRx® 1L system leverages cost-effective disposable bioreactors controlled by an automated controller unit. The controller can manage up to eight (8) docking stations, enabling high-throughput parallel processing and evaluation of multiple cell culture experiments. Designed for perfusion-based workflows, it enhances productivity while minimizing costs, supporting process development, scale-down studies, and data-driven optimization strategies like QbD and DoE.
Pilot-Scale Bioreactors
The CellBRx® 5L bioreactor systems are engineered to facilitate pilot-scale experimentation and intermediate-scale commercial production by providing controlled and scalable culture conditions. These systems offer surface area configurations of 10 m², 25 m², and 40 m², with the 40 m² variant corresponding to approximately 63 units of Cell Factories-10 (CF-10) or 470 units of roller bottles (each 850 cm²). Functioning as a mid-scale stirred bioreactor, the CellBRx® 5L SUB is widely utilized for bioprocess scale-up studies and the optimization of critical physical parameters. These include agitation rate, aeration rate, temperature, pH, and dissolved oxygen concentration, all of which are crucial for maintaining optimal cell growth and productivity.
Large-Scale Bioreactors
The CellBRx® 50L bioreactor systems are optimized for large-scale biologics production, including viral vectors and vaccines. This innovative platform enhances efficiency and reproducibility in adherent cell culture. Available in two configurations—offering 100 m² and 250 m² of culture surface area—the 250 m² variant provides an expansive growth environment equivalent to approximately 393 units of Cell Factories-10 (CF-10) or 2941 units of roller bottles (each 850 cm²). This high surface-to-volume ratio enables significant biologics yield while minimizing spatial requirements compared to conventional culture methods.
Designed for compliance with Good Manufacturing Practice (GMP) standards, Its robust performance and streamlined footprint make it an essential tool for accelerating biologics manufacturing.
Large Industrial-scale Bioreactors
The CellBRx® 200L bioreactor systems represent a breakthrough in large-scale biologics manufacturing, offering exceptional scalability and efficiency. Available in 1000 m² and 1500 m² configurations, the 1500 m² model sets a new industry benchmark, equivalent to approximately 2362 units of Cell Factories-10 (CF-10) or 17,647 roller bottles (850 cm² each). Powered by Dynamic Bed Reactor (DBR) technology, these bioreactors feature a consistently designed cell carrier matrix, maintaining uniformity across scales. This ensures a reproducible process yield, comparable to that of their lower-scale counterparts. With a compact design that maximizes space utilization, the CellBRx® 200L systems reduce capital and operational costs, making them ideal for space-constrained facilities while maintaining top-tier performance in biologics production.
Revolutionizing Adherent Cell Culture with DBR Technology
Scalable bioreactors ideal for inactivated and viral vector-based vaccine production - supporting both research & commercial cGMP operations.
Designed for high-yield production of Lentiviral & AAV vectors, bioreactor systems ensure controlled productivity from bench to clinical scale.
Single-use bioreactors designed for consistent expansion and cell recovery of stem cells in adherent & suspension formats.
Precision-engineered systems tailored for scalable exosome production and harvest, enabling consistent particle yield at large scale.
Versatile bioreactor systems for recombinant protein expression in mammalian hosts, ensuring consistent process control and production yield.
Bioreactors built for scalable production of animal cell-based meat, supporting myoblast, adipocyte, & scaffold-associated tissue growth under cGMP.
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