A groundbreaking innovation in biopharmaceutical manufacturing – CellBRx®-IST is world’s first Fully Integrated, Automated, and Closed-loop system for manufacturing Viral Vectors and Vaccines.
Ready-to-use, pre-sterilized, large-scale assemblies to connect with CellBRx 50L vessel serving as media reservoirs and for perfusion-based biomanufacturing.
Ready-to-use, pre-sterilized bottle assemblies to connect SeedBRx SUBs with Trypsinization assemblies and manifolds.
SCADA-based bioreactor controller powered by Process-To-Gather software, enabling recipe-based process automation for cell growth, trypsinization and cell transfer from BRx to BRx with precise parameter controls and real-time data acquisition.
An integrated bioreactor platform to serve as N-3 seed bioreactor system to inoculate 5L SeedBRx vessel.
Single-use bioreactor vessel designed to offer up to 2.5 m² surface area for efficient seed train expansion at N-3 seed dev stage.
All the Integrated Seed Train SUBs are connected using AseptiQuik® Sterile Connectors (from CPC) for easy and risk-free transfer of media, process fluids and Cells during cell transfer.
An integrated bioreactor platform to serve as N-2 seed bioreactor system to inoculate 10L SeedBRx vessel.
Single-use bioreactor vessel designed to offer up to 25 m² surface area for efficient seed train expansion at N-2 seed dev stage.
Module integrated with SeedBRx docking stations for efficient, automated and close-loop cell detachment and cell harvesting.
An integrated bioreactor platform to serve as N-1 bioreactor system to inoculate 50L production vessel.
A compact, single-use bioreactor vessel offering up to 60 m² surface area for efficient seed train expansion of adherent cells.
A robust, plug-and-play cGMP manufacturing platform engineered for efficient process operations, and seamless integration of the 50L CellBRx SU bioreactor vessel.
A Production-Scale single-use bioreactor vessel with up to 250 m² growth surface area, designed for high-density adherent cell culture in a compact 50L footprint.
Integrated with 50L CellBRx SU bioreactor vessels, this unit enables efficient gas transfer and precise %DO control for optimal cell culture conditions.
Scalable bioreactors ideal for inactivated and viral vector-based vaccine production - supporting both research & commercial cGMP operations.
Designed for high-yield production of Lentiviral & AAV vectors, bioreactor systems ensure controlled productivity from bench to clinical scale.
Single-use bioreactors designed for consistent expansion and cell recovery of stem cells in adherent & suspension formats.
Precision-engineered systems tailored for scalable exosome production and harvest, enabling consistent particle yield at large scale.
Versatile bioreactor systems for recombinant protein expression in mammalian hosts, ensuring consistent process control and production yield.
Bioreactors built for scalable production of animal cell-based meat, supporting myoblast, adipocyte, & scaffold-associated tissue growth under cGMP.
Compared to conventional seed train using 2D multilayer cell stacks, CellBRx-IST can reduce:
