Degree of Homogeneity:
The Unique and dynamic geometry of the CellBRx Bioreactor systems ensures efficient mixing and mass transfer throughout the cultivation matrix. Disc rotations coupled with rotation of curved vans in dynamic bed reactor technology assure the nutritional homogeneity within the vulture vessel and significantly reduce the mixing time. This unique, efficient and stress free mixing pattern in DBR technology makes the CellBRx™ bioreactors the world’s first truly scalable culture devices from 0.5L to 200L culture volume.
Surface area availability per unit:
The available cell culture technologies including Roller bottles, cell factories, multi-plate and packed bed bioreactors provide increased surface area due to the vessel design and/or use of multiple units. The aforesaid technologies suffer from common limitations i.e. efficiency, scalability and affordability. Surface area for cell attachment and growth has been increased drastically with ensured homogenous mixing of media and nutrients along with provision of efficient harvesting of cells using automation.
Process economics:
The innovative DBR technology reduces the cost in the form of capital expenditures, labour, facilities and materials, while increasing protein/cell yield per square foot of production space. Small facility footprints with higher volumetric productivity makes CellBRx™ bioreactors most affordable & preferable tools for biologics production.
Overall efficiency:
CellBRx™ Bioreactors offers the highest overall efficiency in terms of time and production in comparison with other cell culture technologies like Roller bottles, stacked plates, packed bed bioreactors and microcarriers. With the ability to culture and harvest stem cells in aseptic condition, the CellBRx™ systems are the only bioreactor system available for efficient stem cell culture processing.
